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Image Search Results
Journal: International Journal of Neonatal Screening
Article Title: Development of a Multiplex Real-Time PCR Assay for the Newborn Screening of SCID, SMA, and XLA
doi: 10.3390/ijns5040039
Figure Lengend Snippet: Amplification plots for: ( a ) A reference SMA positive sample with three copies of the SMN2 gene showing no amplification of the SMN1 locus; ( b ) an individual over 55 years old (SCID-like) showing no amplification for the TREC locus and normal amplification for the other three targets; ( c ) a contrived SMA, SCID, and XLA positive sample showing amplification only for RPP30. ( d ) A reference SMA carrier sample showing robust amplification of the SMN1 locus.
Article Snippet: Contrived SMA, SCID, and XLA positive samples were made by spiking washed leukocyte depleted blood with
Techniques: Amplification